laser induced breakdown spectroscopy (LIBS); Acoustic Radiation Force Elasticity Microscope(ARFEM); ultrasonic transducer; Femtosecond laser; corneal elasticity;STRENGTH

The nonhomogeneous structure of the cornea suggests a unique spatial distribution of corneal elasticity. Non-invasive measurement of this distribution is critical to understanding how biomechanics control corneal stability and refraction. Femtosecond laser pulses induced optical breakdown and produced cavitation in the anterior and posterior cornea. A confocal ultrasonic transducer applied 6.5 ms acoustic radiation force-chirp bursts to the bubble at 1.5 MHz while monitoring bubble position using pulse-echoes at 20 MHz. The laser induced breakdown spectroscopy (LIBS) were measured in the anterior and posterior cornea to see whether the laser induced plasmas signals will show relationship to Young's modulus.